Searchable abstracts of presentations at key conferences in endocrinology

ea0029p749 | Endocrine Disruptors | ICEECE2012

Octylphenol and triclosan induced proliferation of human breast cancer cells via an estrogen receptor-mediated signaling in vitro

Lee H. , Park M. , Yi B. , Choi K.

The class of endocrine disrupting chemicals (EDCs) is comprised of both naturally occurring and man-made compounds which are structurally similar or distinct to estrogen, and can interfere with the actions of an endogenous steroid hormone via estrogen receptors (ERs). Octylphenol (OP) is alkyl phenol chemical, which is considered to be a low-level endocrine disruptor owing to its tendency to mimic estrogen. It has been reported that triclosan can cause endocrine disruption and...

ea0029p750 | Endocrine Disruptors | ICEECE2012

Endocrine disrupting chemicals induced alteration of cell cycle related genes resulting in proliferation of human breast cancer cells via an estrogen receptor-mediated signaling pathway in vitro

Lee H. , Yi B. , Jeung E. , Choi K.

Endocrine disrupting chemicals (EDCs) have brougt the growing concern about the potential to interfere with the endocrine system and to cause health problems. Among EDCs, bisphenol A (BPA) and 1,1,1-trichloro-2,2-bis(4-methoxyphenol)-ethane (methoxychlor, MXC) can bind to estrogen receptors (ERs) and lead abnormality of ER depenent signaling pathways, resulting in human health problems such as dysfuction of reproduction and carcinogenesis. In this study, we investigated whethe...